4C50

Crystal Structure of the Catalase-Peroxidase (KatG) D137S mutant from Mycobacterium Tuberculosis

Summary for 4C50

Related4C51
DescriptorCATALASE-PEROXIDASE, ALPHA-D-GLUCOSE, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywordsoxidoreductase
Biological sourceMYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains2
Total molecular weight162791.38
Authors
Hersleth, H.-P.,Zhao, X.,Magliozzo, R.S.,Andersson, K.K. (deposition date: 2013-09-10, release date: 2013-11-13, Last modification date: 2013-11-27)
Primary citation
Zhao, X.,Hersleth, H.P.,Zhu, J.,Andersson, K.K.,Magliozzo, R.S.
Access Channel Residues Ser315 and Asp137 in Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) Control Peroxidatic Activation of the Pro-Drug Isoniazid.
Chem.Commun.(Camb.), 49:11650-, 2013
PubMed: 24185282 (PDB entries with the same primary citation)
DOI: 10.1039/C3CC47022A
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.31230.7%3.5%7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution