4C4X

Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9

Summary for 4C4X

Entry DOI	10.2210/pdb4c4x/pdb
Related	4C4Y 4C4Z
Descriptor	BIFUNCTIONAL EPOXIDE HYDROLASE 2, 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea (3 entities in total)
Functional Keywords	hydrolase, drug design, multiple binding modes
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	75208.04
Authors	Pilger, J.,Mazur, A.,Monecke, P.,Schreuder, H.,Elshorst, B.,Langer, T.,Schiffer, A.,Krimm, I.,Wegstroth, M.,Lee, D.,Hessler, G.,Wendt, K.-U.,Becker, S.,Griesinger, C. (deposition date: 2013-09-09, release date: 2014-10-01, Last modification date: 2023-12-20)
Primary citation	Pilger, J.,Mazur, A.,Monecke, P.,Schreuder, H.,Elshorst, B.,Bartoschek, S.,Langer, T.,Schiffer, A.,Krimm, I.,Wegstroth, M.,Lee, D.,Hessler, G.,Wendt, K.,Becker, S.,Griesinger, C. A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54:6511-, 2015 Cited by PubMed: 25877959 DOI: 10.1002/ANIE.201500671 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation