4C4S

Structure of beta-phosphoglucomutase in complex with an alpha- fluorophosphonate analogue of beta-glucose-1-phosphate and magnesium trifluoride

4C4S の概要

• エントリーDOI: 10.2210/pdb4c4s/pdb
• 関連するPDBエントリー: 4C4R 4C4T
• 分子名称: BETA-PHOSPHOGLUCOMUTASE, (1R)-1,5-anhydro-1-[(S)-fluoro(phosphono)methyl]-D-glucitol, TRIFLUOROMAGNESATE, ... (5 entities in total)
• 機能のキーワード: isomerase, phosphoryl transfer, transition state, metal fluoride, mutase
• 由来する生物種: LACTOCOCCUS LACTIS
• 細胞内の位置: Cytoplasm (Potential): P71447
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24621.35

構造登録者

Pellegrini, E.,Bowler, M.W. (登録日: 2013-09-09, 公開日: 2014-07-16, 最終更新日: 2023-12-20)

• 主引用文献: Jin, Y.,Bhattasali, D.,Pellegrini, E.,Forget, S.M.,Baxter, N.J.,Cliff, M.J.,Bowler, M.W.,Jakeman, D.L.,Blackburn, G.M.,Waltho, J.P.; Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction.; Proc.Natl.Acad.Sci.USA, 111:12384-, 2014; PubMed: 25104750; DOI: 10.1073/PNAS.1402850111

実験手法

X-RAY DIFFRACTION (1.5 Å)