4C2N
Crystal structure of human testis angiotensin-I converting enzyme mutant E403R
Summary for 4C2N
Entry DOI | 10.2210/pdb4c2n/pdb |
Related | 4C2O 4C2P 4C2Q 4C2R |
Descriptor | ANGIOTENSIN-CONVERTING ENZYME, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total) |
Functional Keywords | hydrolase, chloride activation, hypertension |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 69270.36 |
Authors | Masuyer, G.,Yates, C.J.,Schwager, S.L.U.,Mohd, A.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2013-08-19, release date: 2013-12-11, Last modification date: 2023-12-20) |
Primary citation | Yates, C.J.,Masuyer, G.,Schwager, S.L.U.,Mohd, A.,Sturrock, E.D.,Acharya, K.R. Molecular and Thermodynamic Mechanisms of the Chloride Dependent Human Angiotensin-I Converting Enzyme (Ace) J.Biol.Chem., 289:1798-, 2014 Cited by PubMed: 24297181DOI: 10.1074/JBC.M113.512335 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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