Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from E. coli.

Summary for 4BY3

DescriptorDIHYDROOROTASE, ZINC ION, FORMIC ACID, ... (4 entities in total)
Functional Keywordshydrolase, de novo pyrimidine biosynthesis, amidohydrolase superfamily, metalloenzyme, zinc binding, histidinate anion
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P27708
Total number of polymer chains1
Total molecular weight43361.76
Ramon-Maiques, S.,Lallous, N.,Grande-Garcia, A. (deposition date: 2013-07-17, release date: 2014-05-28)
Primary citation
Grande-Garcia, A.,Lallous, N.,Diaz-Tejada, C.,Ramon-Maiques, S.
Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22:185-, 2014
PubMed: 24332717 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2013.10.016
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.16631.1%0.7%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution