4BSS

Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form

4BSS の概要

• エントリーDOI: 10.2210/pdb4bss/pdb
• 関連するPDBエントリー: 4BSO 4BSP 4BSR 4BST 4BSU
• 分子名称: LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: signaling protein, adult stem cell, leucine-rich repeat g-protein coupled receptor, leucine-rich repeat, furin domain, wnt signaling, congenital anonychia
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 298875.38

構造登録者

Peng, W.C.,de Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P. (登録日: 2013-06-11, 公開日: 2013-06-19, 最終更新日: 2020-07-29)

• 主引用文献: Peng, W.C.,De Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P.; Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.; Cell Rep., 3:1885-, 2013; PubMed: 23809763; DOI: 10.1016/J.CELREP.2013.06.009

実験手法

X-RAY DIFFRACTION (3.2 Å)