4BK1

Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: H213S mutant in complex with 3-hydroxybenzoate

4BK1 の概要

• エントリーDOI: 10.2210/pdb4bk1/pdb
• 関連するPDBエントリー: 4BJY 4BJZ 4BK2 4BK3
• 分子名称: PROBABLE SALICYLATE MONOOXYGENASE, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, flavoprotein, gentisate, hydroxylase, monooxygenase, phospholipid
• 由来する生物種: RHODOCOCCUS JOSTII
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48729.30

構造登録者

Orru, R.,Montersino, S.,Barendregt, A.,Westphal, A.H.,van Duijn, E.,Mattevi, A.,van Berkel, W.J.H. (登録日: 2013-04-21, 公開日: 2013-07-24, 最終更新日: 2023-12-20)

• 主引用文献: Montersino, S.,Orru, R.,Barendregt, A.,Westphal, A.H.,Van Duijn, E.,Mattevi, A.,Van Berkel, W.J.H.; Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation; J.Biol.Chem., 288:26235-, 2013; PubMed: 23864660; DOI: 10.1074/JBC.M113.479303

実験手法

X-RAY DIFFRACTION (1.73 Å)