4BEI

V. cholera biofilm scaffolding protein RbmA in complex with 18-crown- 6

Summary for 4BEI

• Entry DOI: 10.2210/pdb4bei/pdb
• Related: 4BE5 4BE6
• Descriptor: RBMA, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: cell adhesion, bacterial community
• Biological source: VIBRIO CHOLERAE MJ-1236
• Total number of polymer chains: 8
• Total formula weight: 232107.95

Authors

Maestre-Reyna, M.,Wang, A.H.-J. (deposition date: 2013-03-11, release date: 2013-12-18, Last modification date: 2023-12-20)

Primary citation

Maestre-Reyna, M.,Wu, W.,Wang, A.H.
Structural Insights Into Rbma, a Biofilm Scaffolding Protein of V. Cholerae.
Plos One, 8:82458-, 2013

PubMed Abstract: V. cholerae can form sessile biofilms associated with abiotic surfaces, cyanobacteria, zoo-plankton, mollusks, or crustaceans. Along with the vibrio polysaccharide, secreted proteins of the rbm gene cluster are key to the biofilm ultrastructure. Here we provide a thorough structural characterization of RbmA, a protein involved in mediating cell-cell and cell-biofilm contacts. We correlate our structural findings with initial ligand specificity screening results, NMR protein-ligand interaction analysis, and complement our results with a full biocomputational study.

PubMed: 24340031
DOI: 10.1371/JOURNAL.PONE.0082458

Experimental method

X-RAY DIFFRACTION (2.6 Å)