4BD7
Bax domain swapped dimer induced by octylmaltoside
Summary for 4BD7
Entry DOI | 10.2210/pdb4bd7/pdb |
Related | 4BD2 4BD6 4BD8 4BDU |
Descriptor | APOPTOSIS REGULATOR BAX, PRASEODYMIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | apoptosis, programmed cell death |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Isoform Alpha: Mitochondrion membrane; Single-pass membrane protein. Isoform Beta: Cytoplasm. Isoform Gamma: Cytoplasm. Isoform Delta: Cytoplasm (Potential): Q07812 |
Total number of polymer chains | 4 |
Total formula weight | 77048.11 |
Authors | Czabotar, P.E.,Westphal, D.,Adams, J.M.,Colman, P.M. (deposition date: 2012-10-05, release date: 2013-02-13, Last modification date: 2024-05-08) |
Primary citation | Czabotar, P.E.,Westphal, D.,Dewson, G.,Ma, S.,Hockings, C.,Fairlie, W.D.,Lee, E.F.,Yao, S.,Robin, A.Y.,Smith, B.J.,Huang, D.C.,Kluck, R.M.,Adams, J.M.,Colman, P.M. Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152:519-, 2013 Cited by PubMed: 23374347DOI: 10.1016/J.CELL.2012.12.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.801 Å) |
Structure validation
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