4B6V
The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety
Summary for 4B6V
Entry DOI | 10.2210/pdb4b6v/pdb |
Related | 4B6U |
NMR Information | BMRB: 18663 |
Descriptor | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 (1 entity in total) |
Functional Keywords | translation, m7g cap |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Total number of polymer chains | 1 |
Total formula weight | 22864.07 |
Authors | Osborne, M.J.,Volpon, L.,Kornblatt, J.A.,Culjkovic-Kraljcic, B.,Baguet, A.,Borden, K.L.B. (deposition date: 2012-08-15, release date: 2013-02-27, Last modification date: 2024-06-19) |
Primary citation | Osborne, M.J.,Volpon, L.,Kornblatt, J.A.,Culjkovic-Kraljacic, B.,Baguet, A.,Borden, K.L.B. Eif4E3 Acts as a Tumor Suppressor by Utilizing an Atypical Mode of Methyl-7-Guanosine CAP Recognition. Proc.Natl.Acad.Sci.USA, 110:3877-, 2013 Cited by PubMed: 23431134DOI: 10.1073/PNAS.1216862110 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report