4B53
Crystal structure of the isolated IgG4 CH3 domain
Summary for 4B53
Entry DOI | 10.2210/pdb4b53/pdb |
Related | 1ADQ 4B51 |
Descriptor | IG GAMMA-4 CHAIN C REGION, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | immune system, antibody, immunoglobulin, fab arm exchange, igg1 |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 25044.77 |
Authors | Davies, A.M.,Rispens, T.,den Bleker, T.H.,McDonnell, J.M.,Gould, H.J.,Aalberse, R.C.,Sutton, B.J. (deposition date: 2012-08-02, release date: 2012-12-05, Last modification date: 2023-12-20) |
Primary citation | Davies, A.M.,Rispens, T.,Den Bleker, T.H.,Mcdonnell, J.M.,Gould, H.J.,Aalberse, R.C.,Sutton, B.J. Crystal Structure of the Human Igg4 C(H)3 Dimer Reveals the Role of Arg409 in the Mechanism of Fab-Arm Exchange. Mol.Immunol., 54:1-, 2012 Cited by PubMed: 23164605DOI: 10.1016/J.MOLIMM.2012.10.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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