4B50

Crystal structure of the HIV-1 gp41 MPER-specific llama VHH 2H10

Summary for 4B50

Entry DOI	10.2210/pdb4b50/pdb
Descriptor	2H10 LLAMA VHH (2 entities in total)
Functional Keywords	immune system, neutralizing antibody
Biological source	LAMA GLAMA (LLAMA)
Total number of polymer chains	1
Total formula weight	13351.95
Authors	Lutje Hulsik, D.,Sabin, C.,Macheboeuf, P.,Weissenhorn, W. (deposition date: 2012-08-02, release date: 2013-03-27, Last modification date: 2023-12-20)
Primary citation	Lutje Hulsik, D.,Liu, Y.Y.,Strokappe, N.M.,Battella, S.,El Khattabi, M.,Mccoy, L.E.,Sabin, C.,Hinz, A.,Hock, M.,Macheboeuf, P.,Bonvin, A.M.,Langedijk, J.P.,Davis, D.,Forsman Quigley, A.,Aasa-Chapman, M.M.,Seaman, M.S.,Ramos, A.,Poignard, P.,Favier, A.,Simorre, J.P.,Weiss, R.A.,Verrips, C.T.,Weissenhorn, W.,Rutten, L. A Gp41 Mper-Specific Llama Vhh Requires a Hydrophobic Cdr3 for Neutralization But not for Antigen Recognition. Plos Pathog., 9:3202-, 2013 Cited by PubMed: 23505368 DOI: 10.1371/JOURNAL.PPAT.1003202 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation