4B18
The crystal structure of human Importin alpha 5 with TERT NLS peptide
Summary for 4B18
Entry DOI | 10.2210/pdb4b18/pdb |
Related | 2BCK 2JDQ |
Descriptor | IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE (3 entities in total) |
Functional Keywords | transport protein - peptide complex, transport protein / peptide |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm : P52294 Nucleus, nucleolus: O14746 |
Total number of polymer chains | 2 |
Total formula weight | 51684.03 |
Authors | |
Primary citation | Jeong, S.A.,Kim, K.,Lee, J.H.,Cha, J.S.,Khadka, P.,Cho, H.,Chung, I.K. Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation. J.Cell.Sci., 128:2287-, 2015 Cited by PubMed: 25999477DOI: 10.1242/JCS.166132 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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