4AXB

Crystal structure of soman-aged human butyrylcholinesterase in complex with 2-PAM

Summary for 4AXB

Entry DOI	10.2210/pdb4axb/pdb
Descriptor	CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, ... (9 entities in total)
Functional Keywords	hydrolase, aging
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	62364.36
Authors	Wandhammer, M.,de Koning, M.,Noort, D.,Goeldner, M.,Nachon, F. (deposition date: 2012-06-12, release date: 2012-08-29, Last modification date: 2023-12-20)
Primary citation	Wandhammer, M.,De Koning, M.,Van Grol, M.,Loiodice, M.,Saurel, L.,Noort, D.,Goeldner, M.,Nachon, F. A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase Chem.Biol.Interact, 203:19-, 2013 Cited by PubMed: 22922115 DOI: 10.1016/J.CBI.2012.08.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation