4AXB

Crystal structure of soman-aged human butyrylcholinesterase in complex with 2-PAM

4AXB の概要

• エントリーDOI: 10.2210/pdb4axb/pdb
• 分子名称: CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, POTASSIUM ION, ... (9 entities in total)
• 機能のキーワード: hydrolase, aging
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62364.36

構造登録者

Wandhammer, M.,de Koning, M.,Noort, D.,Goeldner, M.,Nachon, F. (登録日: 2012-06-12, 公開日: 2012-08-29, 最終更新日: 2023-12-20)

• 主引用文献: Wandhammer, M.,De Koning, M.,Van Grol, M.,Loiodice, M.,Saurel, L.,Noort, D.,Goeldner, M.,Nachon, F.; A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase; Chem.Biol.Interact, 203:19-, 2013; PubMed: 22922115; DOI: 10.1016/J.CBI.2012.08.005

実験手法

X-RAY DIFFRACTION (2.4 Å)