4ATT

FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl para methoxy phenyl

4ATT の概要

• エントリーDOI: 10.2210/pdb4att/pdb
• 分子名称: FIMH, 3-(4-methoxyphenyl)prop-2-yn-1-yl alpha-D-mannopyranoside (3 entities in total)
• 機能のキーワード: sugar binding protein, fimbriae, variable immunoglobulin fold, urinary tract infection
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17241.15

構造登録者

Bouckaert, J.,Touaibia, M.,Roos, G.,Shiao, T.C.,Wang, Q.,Papadopoulos, A.,Roy, R. (登録日: 2012-05-09, 公開日: 2013-05-22, 最終更新日: 2023-12-20)

• 主引用文献: Roos, G.,Wellens, A.,Touaibia, M.,Yamakawa, N.,Geerlings, P.,Roy, R.,Wyns, L.,Bouchaert, J.; Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of Fimh.; Acs Med.Chem.Lett., 4:1085-, 2013; PubMed: 24900609; DOI: 10.1021/ML400269V

実験手法

X-RAY DIFFRACTION (1.251 Å)