4AR8

Crystal structure of the peptidase domain of collagenase T from Clostridium tetani complexed with the peptidic inhibitor isoamyl- phosphonyl-Gly-Pro-Ala at 2.05 angstrom resolution.

4AR8 の概要

• エントリーDOI: 10.2210/pdb4ar8/pdb
• 関連するPDBエントリー: 4AR9
• 分子名称: COLLAGENASE COLT, ISOAMYL-PHOSPHONYL-GLY-PRO-ALA, ZINC ION, ... (5 entities in total)
• 機能のキーワード: hydrolase-inhibitor complex, collagenolysis, metalloprotease, peptidase, hydrolase, hydrolase/inhibitor
• 由来する生物種: CLOSTRIDIUM TETANI; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 92495.32

構造登録者

Eckhard, U.,Brandstetter, H. (登録日: 2012-04-21, 公開日: 2013-06-05, 最終更新日: 2023-12-20)

• 主引用文献: Eckhard, U.,Schonauer, E.,Brandstetter, H.; Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T.; J.Biol.Chem., 288:20184-, 2013; PubMed: 23703618; DOI: 10.1074/JBC.M112.448548

実験手法

X-RAY DIFFRACTION (2.05 Å)