4ABN

Crystal structure of full length mouse Strap (TTC5)

Summary for 4ABN

• Entry DOI: 10.2210/pdb4abn/pdb
• Descriptor: TETRATRICOPEPTIDE REPEAT PROTEIN 5, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: p53 cofactor, stress-response, dna repair, gene regulation
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Nucleus: Q99LG4
• Total number of polymer chains: 2
• Total formula weight: 104940.20

Authors

Pike, A.C.W.,Bullock, A.N.,Kleinekofort, W.,Zimmermann, T.,Burgess-Brown, N.,Sharpe, T.D.,Thangaratnarajah, C.,Keates, T.,Ugochukwu, E.,Bunkoczi, G.,Uppenberg, J.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,La Thangue, N.B.,Knapp, S. (deposition date: 2011-12-09, release date: 2012-01-25, Last modification date: 2024-05-08)

• Primary citation: Adams, C.J.,Pike, A.C.,Maniam, S.,Sharpe, T.D.,Coutts, A.S.,Knapp, S.,La Thangue, N.B.,Bullock, A.N.; The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure.; Proc.Natl.Acad.Sci.USA, 109:3778-, 2012; PubMed: 22362889; DOI: 10.1073/PNAS.1113731109

Experimental method

X-RAY DIFFRACTION (2.05 Å)