4A5W

Crystal structure of C5b6

Summary for 4A5W

Related1CFA 1KJS 1XWE
EMDB information1991
DescriptorCOMPLEMENT C5, COMPLEMENT COMPONENT C6, N-ACETYL-D-GLUCOSAMINE, ... (6 entities in total)
Functional Keywordsimmune system, immunity, membrane attack complex
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P01031 P13671
Total number of polymer chains2
Total molecular weight281878.24
Authors
Hadders, M.A.,Bubeck, D.,Forneris, F.,Pangburn, M.,Llorca, O.,Lea, S.M.,Gros, P. (deposition date: 2011-10-28, release date: 2012-03-14, Last modification date: 2012-10-31)
Primary citation
Hadders, M.A.,Bubeck, D.,Roversi, P.,Hakobyan, S.,Forneris, F.,Morgan, B.P.,Pangburn, M.K.,Llorca, O.,Lea, S.M.,Gros, P.
Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1:200-, 2012
PubMed: 22832194 (PDB entries with the same primary citation)
DOI: 10.1016/J.CELREP.2012.02.003
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.5 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.310101.2%6.3%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution