4A2S

Structure of the engineered retro-aldolase RA95.5

Summary for 4A2S

• Entry DOI: 10.2210/pdb4a2s/pdb
• Related: 1A53 1IGS 1JUK 1JUL 1LBF 1LBL 2C3Z 4A2R
• Descriptor: INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE, 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE (3 entities in total)
• Functional Keywords: lyase, engineered enzyme, directed evolution
• Biological source: SULFOLOBUS SOLFATARICUS
• Total number of polymer chains: 1
• Total formula weight: 30233.84

Authors

Giger, L.,Caner, S.,Kast, P.,Baker, D.,Ban, N.,Hilvert, D. (deposition date: 2011-09-28, release date: 2012-11-07, Last modification date: 2023-12-20)

• Primary citation: Giger, L.,Caner, S.,Obexer, R.,Kast, P.,Baker, D.,Ban, N.,Hilvert, D.; Evolution of a designed retro-aldolase leads to complete active site remodeling.; Nat.Chem.Biol., 9:494-498, 2013; PubMed: 23748672; DOI: 10.1038/nchembio.1276

Experimental method

X-RAY DIFFRACTION (1.4 Å)