4A29

Structure of the engineered retro-aldolase RA95.0

Summary for 4A29

• Entry DOI: 10.2210/pdb4a29/pdb
• Descriptor: ENGINEERED RETRO-ALDOL ENZYME RA95.0, 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, D-MALATE, ... (4 entities in total)
• Functional Keywords: de novo protein, engineered enzyme, retro-aldolase, directed evolution
• Biological source: SYNTHETIC CONSTRUCT
• Total number of polymer chains: 1
• Total formula weight: 30086.58

Authors

Giger, L.,Caner, S.,Kast, P.,Baker, D.,Ban, N.,Hilvert, D. (deposition date: 2011-09-23, release date: 2012-11-07, Last modification date: 2023-12-20)

• Primary citation: Giger, L.,Caner, S.,Obexer, R.,Kast, P.,Baker, D.,Ban, N.,Hilvert, D.; Evolution of a designed retro-aldolase leads to complete active site remodeling.; Nat.Chem.Biol., 9:494-498, 2013; PubMed: 23748672; DOI: 10.1038/nchembio.1276

Experimental method

X-RAY DIFFRACTION (1.1 Å)