4D3M
Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(2-(4-methyl-6-(methylamino)pyridin-2-yl)ethyl)benzonitrile
Summary for 4D3M
Entry DOI | 10.2210/pdb4d3m/pdb |
Related | 4D3I 4D3J 4D3K 4D3N 4D3O |
Descriptor | NITRIC OXIDE SYNTHASE OXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | oxidoreductase, inhibitor |
Biological source | BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168 |
Total number of polymer chains | 1 |
Total formula weight | 43036.81 |
Authors | Holden, J.K.,Poulos, T.L. (deposition date: 2014-10-23, release date: 2015-01-14, Last modification date: 2023-12-20) |
Primary citation | Holden, J.K.,Kang, S.,Hollingsworth, S.A.,Li, H.,Lim, N.,Chen, S.,Huang, H.,Xue, F.,Tang, W.,Silverman, R.B.,Poulos, T.L. Structure-based design of bacterial nitric oxide synthase inhibitors. J. Med. Chem., 58:994-1004, 2015 Cited by PubMed: 25522110DOI: 10.1021/jm501723p PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.741 Å) |
Structure validation
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