484D
SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX
Summary for 484D
| Entry DOI | 10.2210/pdb484d/pdb |
| Descriptor | RNA APTAMER, BASIC REV PEPTIDE (2 entities in total) |
| Functional Keywords | hiv-1 rev peptide; rna aptamer; bound peptide secondary structure, peptide- binding rna, tertiary architectures, adaptive-binding, rna binding protein-rna complex, rna binding protein/rna |
| Total number of polymer chains | 2 |
| Total formula weight | 11145.99 |
| Authors | Ye, X.,Gorin, A.A.,Frederick, R.,Hu, W.,Majumdar, A.,Xu, W.,Mclendon, G.,Ellington, A.,Patel, D.J. (deposition date: 1999-08-02, release date: 1999-10-14, Last modification date: 2023-12-27) |
| Primary citation | Ye, X.,Gorin, A.,Frederick, R.,Hu, W.,Majumdar, A.,Xu, W.,McLendon, G.,Ellington, A.,Patel, D.J. RNA architecture dictates the conformations of a bound peptide. Chem.Biol., 6:657-669, 1999 Cited by PubMed Abstract: The biological function of several viral and bacteriophage proteins, and their arginine-rich subdomains, involves RNA-mediated interactions. It has been shown recently that bound peptides adopt either beta-hairpin or alpha-helical conformations in viral and phage peptide-RNA complexes. We have compared the structures of the arginine-rich peptide domain of HIV-1 Rev bound to two RNA aptamers to determine whether RNA architecture can dictate the conformations of a bound peptide. PubMed: 10467126DOI: 10.1016/S1074-5521(99)80117-3 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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