459D

DNA MINOR-GROOVE RECOGNITION OF A TRIS-BENZIMIDAZOLE DRUG

Summary for 459D

• Entry DOI: 10.2210/pdb459d/pdb
• Descriptor: DNA (5'-D(*CP*GP*(CBR)P*AP*TP*AP*TP*TP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*AP*TP*GP*CP*G)-3'), 2''-(4-METHOXYPHENYL)-5-(3-AMINO-1-PYRROLIDINYL)-2,5',2',5''-TRI-BENZIMIDAZOLE, ... (4 entities in total)
• Functional Keywords: minor groove binding, b-dna, complexed with tris-benzimidazole, deoxyribonucleic acid, dna
• Total number of polymer chains: 2
• Total formula weight: 7945.33

Authors

Aymami, J.,Nunn, C.M.,Neidle, S. (deposition date: 1999-03-10, release date: 1999-06-28, Last modification date: 2023-12-27)

• Primary citation: Aymami, J.,Nunn, C.M.,Neidle, S.; DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand.; Nucleic Acids Res., 27:2691-2698, 1999; PubMed: 10373586; DOI: 10.1093/nar/27.13.2691

Experimental method

X-RAY DIFFRACTION (2.3 Å)