413D

A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)

「373D」から置き換えられました

413D の概要

• エントリーDOI: 10.2210/pdb413d/pdb
• 分子名称: RNA (5'-R(*UP*GP*AP*GP*CP*UP*UP*CP*GP*GP*CP*UP*C)-3') (2 entities in total)
• 機能のキーワード: a'-rna, double helix, rna
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4110.46

構造登録者

Tanaka, Y.,Fujii, S.,Hiroaki, H.,Sakata, T.,Tanaka, T.,Uesugi, S.,Tomita, K.-I.,Kyogoku, Y. (登録日: 1998-07-10, 公開日: 1998-07-10, 最終更新日: 2024-02-28)

主引用文献

Tanaka, Y.,Fujii, S.,Hiroaki, H.,Sakata, T.,Tanaka, T.,Uesugi, S.,Tomita, K.,Kyogoku, Y.
A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC).
Nucleic Acids Res., 27:949-955, 1999

PubMed Abstract: Here we demonstrate the presence of the A'-RNA conformation using the single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average A'-RNA conformation deduced from X-ray fiber diffraction data had only been available previously, but now the presence of the A'-RNA conformation has been found in a single crystal structure for the first time. Statistical analysis showed that the A'-RNA conformation is distinguishable from the A-RNA conformation in a plot of the major groove width against the base pair inclination angle. The major groove of the A'-RNA conformation is wide enough to accommodate a protein or peptide while that of the A-RNA conformation is too narrow to do so. The presence of the A'-RNA conformation is significant for protein-RNA interaction.

PubMed: 9927725
DOI: 10.1093/nar/27.4.949

実験手法

X-RAY DIFFRACTION (1.8 Å)