407D

STRUCTURAL BASIS FOR RECOGNITION OF A-T AND T-A BASE PAIRS IN THE MINOR GROOVE OF B-DNA

407D の概要

• エントリーDOI: 10.2210/pdb407d/pdb
• 分子名称: DNA (5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*G)-3'), ~{N}-[5-[[5-[[5-[[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]carbamoyl]-1-methyl-pyrrol-3-yl]carbamoyl]-1-methyl-pyrrol-3-yl]carbamoyl]-1-methyl-4-oxidanyl-pyrrol-3-yl]-1-methyl-imidazole-2-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: drugs in the dna minor groove, dna
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7539.60

構造登録者

Rees, D.C. (登録日: 1998-06-24, 公開日: 1998-10-19, 最終更新日: 2024-02-28)

• 主引用文献: Kielkopf, C.L.,White, S.,Szewczyk, J.W.,Turner, J.M.,Baird, E.E.,Dervan, P.B.,Rees, D.C.; A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.; Science, 282:111-115, 1998; PubMed: 9756473; DOI: 10.1126/science.282.5386.111

実験手法

X-RAY DIFFRACTION (2.2 Å)