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3ZT0

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design

Summary for 3ZT0
Entry DOI10.2210/pdb3zt0/pdb
Related1HYV 1HYZ 3ZSO 3ZSQ 3ZSR 3ZSV 3ZSW 3ZSX 3ZSY 3ZSZ 3ZT1 3ZT2 3ZT3 3ZT4
DescriptorINTEGRASE, SULFATE ION, (4-CARBOXY-1,3-BENZODIOXOL-5-YL)-N-{2-[(4-METHOXYBENZYL)CARBAMOYL]BENZYL}-N-METHYLMETHANAMINIUM, ... (4 entities in total)
Functional Keywordstransferase, aids
Biological sourceHUMAN IMMUNODEFICIENCY VIRUS
Total number of polymer chains2
Total formula weight38295.07
Authors
Primary citationPeat, T.S.,Rhodes, D.I.,Vandegraaff, N.,Le, G.,Smith, J.A.,Clark, L.J.,Jones, E.D.,Coates, J.A.V.,Thienthong, N.,Newman, J.,Dolezal, O.,Mulder, R.,Ryan, J.H.,Savage, G.P.,Francis, C.L.,Deadman, J.J.
Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7:40147-, 2012
Cited by
PubMed: 22808106
DOI: 10.1371/JOURNAL.PONE.0040147
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

217705

数据于2024-03-27公开中

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