3ZL4

Antibody structural organization: Role of kappa - lambda chain constant domain switch in catalytic functionality

Summary for 3ZL4

Entry DOI	10.2210/pdb3zl4/pdb
Descriptor	A17 ANTIBODY FAB FRAGMENT HEAVY CHAIN, A17 ANTIBODY FAB FRAGMENT LAMBDA LIGHT CHAIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	immune system
Biological source	Homo sapiens (HUMAN) More
Total number of polymer chains	2
Total formula weight	53726.28
Authors	Chatziefthimiou, S.D.,Ponomarenko, N.A.,Kurkova, I.N.,Smirnov, A.V.,Smirnov, I.V.,Lamzin, V.S.,Gabibov, A.G.,Wilmanns, M. (deposition date: 2013-01-28, release date: 2014-02-05, Last modification date: 2023-12-20)
Primary citation	Ponomarenko, N.A.,Chatziefthimiou, S.D.,Kurkova, I.N.,Mokrushina, Y.A.,Stepanova, A.V.,Smirnov, I.V.,Avakyan, E.M.,Bobik, T.V.,Mamedov, A.,Mitkevich, V.A.,Belogurov, A.J.,Fedorova, O.S.,Dubina, M.,Golovin, A.,Lamzin, V.S.,Friboulet, A.,Makarov, A.A.,Wilmanns, M.,Gabibov, A.G. Role of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody Acta Crystallogr.,Sect.D, 70:708-, 2014 Cited by PubMed: 24598740 DOI: 10.1107/S1399004713032446 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation