3ZL4

Antibody structural organization: Role of kappa - lambda chain constant domain switch in catalytic functionality

3ZL4 の概要

• エントリーDOI: 10.2210/pdb3zl4/pdb
• 分子名称: A17 ANTIBODY FAB FRAGMENT HEAVY CHAIN, A17 ANTIBODY FAB FRAGMENT LAMBDA LIGHT CHAIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: immune system
• 由来する生物種: Homo sapiens (HUMAN); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53726.28

構造登録者

Chatziefthimiou, S.D.,Ponomarenko, N.A.,Kurkova, I.N.,Smirnov, A.V.,Smirnov, I.V.,Lamzin, V.S.,Gabibov, A.G.,Wilmanns, M. (登録日: 2013-01-28, 公開日: 2014-02-05, 最終更新日: 2023-12-20)

• 主引用文献: Ponomarenko, N.A.,Chatziefthimiou, S.D.,Kurkova, I.N.,Mokrushina, Y.A.,Stepanova, A.V.,Smirnov, I.V.,Avakyan, E.M.,Bobik, T.V.,Mamedov, A.,Mitkevich, V.A.,Belogurov, A.J.,Fedorova, O.S.,Dubina, M.,Golovin, A.,Lamzin, V.S.,Friboulet, A.,Makarov, A.A.,Wilmanns, M.,Gabibov, A.G.; Role of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody; Acta Crystallogr.,Sect.D, 70:708-, 2014; PubMed: 24598740; DOI: 10.1107/S1399004713032446

実験手法

X-RAY DIFFRACTION (1.95 Å)