3ZL1
A thiazolyl-mannoside bound to FimH, monoclinic space group
Summary for 3ZL1
Entry DOI | 10.2210/pdb3zl1/pdb |
Related | 3ZL2 |
Descriptor | PROTEIN FIMH, N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | cell adhesion, type-1 fimbriae, thiazole, crohn's disease, immunoglobulin |
Biological source | ESCHERICHIA COLI |
Cellular location | Fimbrium: P08191 |
Total number of polymer chains | 2 |
Total formula weight | 34477.75 |
Authors | Brument, S.,Sivignon, A.,Dumych, T.I.,Moreau, N.,Roos, G.,Guerardel, Y.,Chalopin, T.,Deniaud, D.,Bilyy, R.O.,Darfeuille-Michaud, A.,Bouckaert, J.,Gouin, S.G. (deposition date: 2013-01-27, release date: 2013-07-10, Last modification date: 2023-12-20) |
Primary citation | Brument, S.,Sivignon, A.,Dumych, T.I.,Moreau, N.,Roos, G.,Guerardel, Y.,Chalopin, T.,Deniaud, D.,Bilyy, R.O.,Darfeuille-Michaud, A.,Bouckaert, J.,Gouin, S.G. Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem., 56:5395-, 2013 Cited by PubMed: 23795713DOI: 10.1021/JM400723N PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.551 Å) |
Structure validation
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