3ZGG

Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group)

3ZGG の概要

• エントリーDOI: 10.2210/pdb3zgg/pdb
• 関連するPDBエントリー: 3ZGF
• 分子名称: HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: transferase, glycosyltransferases, catalytic domain
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35503.47

構造登録者

Jorgensen, R.,Batot, G.O.,Hindsgaul, O.,Tanaka, H.,Perez, S.,Imberty, A.,Breton, C.,Royant, A.,Palcic, M.M. (登録日: 2012-12-17, 公開日: 2014-01-15, 最終更新日: 2023-12-20)

• 主引用文献: Jorgensen, R.,Batot, G.,Mannerstedt, K.,Imberty, A.,Breton, C.,Hindsgaul, O.,Royant, A.,Palcic, M.M.; Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations; Acta Crystallogr.,Sect.F, 70:1015-, 2014; PubMed: 25084373; DOI: 10.1107/S2053230X1401259X

実験手法

X-RAY DIFFRACTION (1.9 Å)