3ZCM
Small molecule inhibitors of the LEDGF site of HIV integrase identified by fragment screening and structure based design.
Summary for 3ZCM
Entry DOI | 10.2210/pdb3zcm/pdb |
Descriptor | HIV INTEGRASE, SULFATE ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | transferase |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS |
Total number of polymer chains | 2 |
Total formula weight | 38647.40 |
Authors | Peat, T.S. (deposition date: 2012-11-21, release date: 2012-12-05, Last modification date: 2023-12-20) |
Primary citation | Peat, T.S.,Rhodes, D.I.,Vandegraaff, N.,Le, G.,Smith, J.A.,Clark, L.J.,Jones, E.D.,Coates, J.A.V.,Thienthong, N.,Newman, J.,Dolezal, O.,Mulder, R.,Ryan, J.H.,Savage, G.P.,Francis, C.L.,Deadman, J.J. Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design. Plos One, 7:40147-, 2012 Cited by PubMed: 22808106DOI: 10.1371/JOURNAL.PONE.0040147 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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