3WWK

Crystal structure of CLEC-2 in complex with rhodocytin

Summary for 3WWK

• Entry DOI: 10.2210/pdb3wwk/pdb
• Related: 3WSR
• Descriptor: C-type lectin domain family 1 member B, Snaclec rhodocytin subunit alpha, Snaclec rhodocytin subunit beta (3 entities in total)
• Functional Keywords: c-type lectin fold, carbohydrate binding, podoplanin, rhodocytin, sugar binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane ; Single-pass type II membrane protein : Q9P126; Secreted: Q9I841 Q9I840
• Total number of polymer chains: 12
• Total formula weight: 191038.08

Authors

Nagae, M.,Morita-Matsumoto, K.,Kato, M.,Kato-Kaneko, M.,Kato, Y.,Yamaguchi, Y. (deposition date: 2014-06-20, release date: 2014-10-22, Last modification date: 2023-11-08)

• Primary citation: Nagae, M.,Morita-Matsumoto, K.,Kato, M.,Kato-Kaneko, M.,Kato, Y.,Yamaguchi, Y.; A Platform of C-type Lectin-like Receptor CLEC-2 for Binding O-Glycosylated Podoplanin and Nonglycosylated Rhodocytin; Structure, 22:1711-1721, 2014; PubMed: 25458834; DOI: 10.1016/j.str.2014.09.009

Experimental method

X-RAY DIFFRACTION (2.98 Å)