3WTQ

Crystal structure of VDR-LBD complexed with 22S-butyl-2-methylidene-19-nor-1a,25-dihydroxyvitamin D3

Summary for 3WTQ

• Entry DOI: 10.2210/pdb3wtq/pdb
• Descriptor: Vitamin D3 receptor, Mediator of RNA polymerase II transcription subunit 1, (1R,3R,7E,17beta)-17-[(2R,3S)-3-butyl-6-hydroxy-6-methylheptan-2-yl]-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, ... (4 entities in total)
• Functional Keywords: transcription, vitamin d3, vdre, rxr, co-factors
• Biological source: Rattus norvegicus (brown rat,rat,rats); More
• Cellular location: Nucleus: P13053 Q15648
• Total number of polymer chains: 2
• Total formula weight: 32638.68

Authors

Nakabayashi, M.,Inaba, Y.,Itoh, T.,Anami, Y.,Ikura, T.,Ito, N.,Yamamoto, K. (deposition date: 2014-04-15, release date: 2015-04-15, Last modification date: 2024-03-20)

• Primary citation: Nakabayashi, M.,Inaba, Y.,Itoh, T.,Anami, Y.,Ikura, T.,Ito, N.,Yamamoto, K.; Crystal structure of VDR-LBD complexed with 22S-butyl-2-methylidene-19-nor-1a,25-dihydroxyvitamin D3; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)