3WKN

Crystal structure of the artificial protein AFFinger p17 (AF.p17) complexed with Fc fragment of human IgG

3WKN の概要

• エントリーDOI: 10.2210/pdb3wkn/pdb
• 分子名称: Ig gamma-1 chain C region, AFFinger p17, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: immunoglobulin-like beta-sandwich, binding protein, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01857
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 253785.25

構造登録者

Watanabe, H.,Honda, S. (登録日: 2013-10-29, 公開日: 2014-10-29, 最終更新日: 2022-08-24)

• 主引用文献: Watanabe, H.,Honda, S.; Adaptive Assembly: Maximizing the Potential of a Given Functional Peptide with a Tailor-Made Protein Scaffold.; Chem.Biol., 22:1165-1173, 2015; PubMed: 26299673; DOI: 10.1016/j.chembiol.2015.07.015

実験手法

X-RAY DIFFRACTION (2.9 Å)