3WE1

Crystal structure of Dengue 4 Envelope protein domain III (ED3)

3WE1 の概要

• エントリーDOI: 10.2210/pdb3we1/pdb
• 分子名称: Envelope protein E (2 entities in total)
• 機能のキーワード: immunoglobulin like domain, cell surface receptor binding, represent epitope, virus surface, structural protein, immune system
• 由来する生物種: Dengue virus type 4 (DENV-4)
• 細胞内の位置: Capsid protein C: Virion . Peptide pr: Secreted . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Multi-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P09866
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22954.16

構造登録者

Elahi, M.,Islam, M.M.,Noguchi, K.,Yohda, M.,Toh, H.,Kuroda, Y. (登録日: 2013-06-27, 公開日: 2014-01-22, 最終更新日: 2023-11-08)

• 主引用文献: Elahi, M.,Islam, M.M.,Noguchi, K.,Yohda, M.,Toh, H.,Kuroda, Y.; Computational prediction and experimental characterization of a "size switch type repacking" during the evolution of dengue envelope protein domain III (ED3).; Biochim.Biophys.Acta, 1844:585-592, 2014; PubMed: 24373879; DOI: 10.1016/j.bbapap.2013.12.013

実験手法

X-RAY DIFFRACTION (2.278 Å)