3WD2

Serratia marcescens Chitinase B complexed with azide inhibitor

Summary for 3WD2

Entry DOI	10.2210/pdb3wd2/pdb
Related	3WD0 3WD1 3WD3 3WD4
Descriptor	Chitinase B, [2-[[(2S)-1-[bis(phenylmethyl)amino]-5-[[N-(methylcarbamoyl)carbamimidoyl]amino]-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-diazonio-azanide, GLYCEROL, ... (6 entities in total)
Functional Keywords	tim barrel, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Serratia marcescens
Total number of polymer chains	1
Total formula weight	57592.17
Authors	Hirose, T.,Maita, N.,Gouda, H.,Koseki, J.,Yamamoto, T.,Sugawara, A.,Nakano, H.,Hirono, S.,Shiomi, K.,Watanabe, T.,Taniguchi, H.,Sharpless, K.B.,Omura, S.,Sunazuka, T. (deposition date: 2013-06-06, release date: 2013-09-18, Last modification date: 2023-11-08)
Primary citation	Hirose, T.,Maita, N.,Gouda, H.,Koseki, J.,Yamamoto, T.,Sugawara, A.,Nakano, H.,Hirono, S.,Shiomi, K.,Watanabe, T.,Taniguchi, H.,Sharpless, K.B.,Omura, S.,Sunazuka, T. Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Proc.Natl.Acad.Sci.USA, 110:15892-15897, 2013 Cited by PubMed: 24043811 DOI: 10.1073/pnas.1315049110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation