3WAV
Crystal Structure of Autotaxin in Complex with Compound 10
Summary for 3WAV
Entry DOI | 10.2210/pdb3wav/pdb |
Related | 3WAW 3WAX 3WAY |
Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, SULFATE ION, (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, ... (12 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 1 |
Total formula weight | 99597.90 |
Authors | Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2013-05-09, release date: 2013-07-31, Last modification date: 2023-11-08) |
Primary citation | Kawaguchi, M.,Okabe, T.,Okudaira, S.,Nishimasu, H.,Ishitani, R.,Kojima, H.,Nureki, O.,Aoki, J.,Nagano, T. Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8:1713-1721, 2013 Cited by PubMed: 23688339DOI: 10.1021/cb400150c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.797 Å) |
Structure validation
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