3WAI

Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (AfAglB-L, O29867_ARCFU) from Archaeoglobus fulgidus as a MBP fusion

3WAI の概要

• エントリーDOI: 10.2210/pdb3wai/pdb
• 関連するPDBエントリー: 3WAJ 3WAK
• 分子名称: Maltose-binding periplasmic protein, Transmembrane oligosaccharyl transferase (2 entities in total)
• 機能のキーワード: oligosaccharyltransferase, n-glycosylation, mbp fusion, gt-c, protein b-oligosaccharyltransferase, transferase, transport protein
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 82973.31

構造登録者

Matsumoto, S.,Shimada, A.,Kohda, D. (登録日: 2013-05-03, 公開日: 2013-07-17, 最終更新日: 2023-11-08)

主引用文献

Matsumoto, S.,Shimada, A.,Kohda, D.
Crystal structure of the C-terminal globular domain of the third paralog of the Archaeoglobus fulgidus oligosaccharyltransferases
Bmc Struct.Biol., 13:11-11, 2013

PubMed Abstract: Protein N-glycosylation occurs in the three domains of life. Oligosaccharyltransferase (OST) transfers an oligosaccharide chain to the asparagine residue in the N-glycosylation sequons. The catalytic subunits of the OST enzyme are STT3 in eukaryotes, AglB in archaea and PglB in eubacteria. The genome of a hyperthermophilic archaeon, Archaeoglobus fulgidus, encodes three paralogous AglB proteins. We previously solved the crystal structures of the C-terminal globular domains of two paralogs, AglB-Short 1 and AglB-Short 2.

PubMed: 23815857
DOI: 10.1186/1472-6807-13-11

実験手法

X-RAY DIFFRACTION (1.897 Å)