3W9I

Structural basis for the inhibition of bacterial multidrug exporters

Summary for 3W9I

• Entry DOI: 10.2210/pdb3w9i/pdb
• Related: 3W9H 3W9J
• Descriptor: Multidrug resistance protein MexB, DODECYL-BETA-D-MALTOSIDE (3 entities in total)
• Functional Keywords: mexb, efflux pump, transporter, multidrug efflux pump, mexa, oprm, inner membrane, transport protein, membrane protein
• Biological source: Pseudomonas aeruginosa
• Cellular location: Cell inner membrane; Multi-pass membrane protein: P52002
• Total number of polymer chains: 6
• Total formula weight: 685432.82

Authors

Sakurai, K.,Nakashima, R.,Hayashi, K.,Yamaguchi, A. (deposition date: 2013-04-04, release date: 2013-07-03, Last modification date: 2023-11-08)

• Primary citation: Nakashima, R.,Sakurai, K.,Yamasaki, S.,Hayashi, K.,Nagata, C.,Hoshino, K.,Onodera, Y.,Nishino, K.,Yamaguchi, A.; Structural basis for the inhibition of bacterial multidrug exporters; Nature, 500:102-106, 2013; PubMed: 23812586; DOI: 10.1038/nature12300

Experimental method

X-RAY DIFFRACTION (2.71 Å)