3W8V

Crystal Structure Analysis of the synthetic GCN4 coiled coil peptide

3W8V の概要

• エントリーDOI: 10.2210/pdb3w8v/pdb
• 関連するPDBエントリー: 3W92 3W93
• 分子名称: GCN4n coiled coil peptide, PARA ACETAMIDO BENZOIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: transcription
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 11779.08

構造登録者

Shahar, A.,Zarivach, R.,Ashkenasy, G. (登録日: 2013-03-21, 公開日: 2014-02-12, 最終更新日: 2023-11-08)

主引用文献

Dadon, Z.,Samiappan, M.,Shahar, A.,Zarivach, R.,Ashkenasy, G.
A high-resolution structure that provides insight into coiled-coil thiodepsipeptide dynamic chemistry
Angew.Chem.Int.Ed.Engl., 52:9944-9947, 2013

PubMed Abstract: Stable and reactive: A crystal structure at 1.35 Å of a thioester coiled-coil protein reveals high similarity to all-peptide-bond proteins. In these assemblies, the thioester bonds are kept reactive towards thiol molecules in the mixture. This enables efficient domain exchange between proteins in response to changes in folding conditions or introduction of external templates.

PubMed: 23929823
DOI: 10.1002/anie.201303900

実験手法

X-RAY DIFFRACTION (2.1 Å)