Summary for 3W55
Entry DOI | 10.2210/pdb3w55/pdb |
Descriptor | Mitogen-activated protein kinase 1, (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione (3 entities in total) |
Functional Keywords | protein kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P28482 |
Total number of polymer chains | 1 |
Total formula weight | 42593.81 |
Authors | Ohori, M.,Kinoshita, T. (deposition date: 2013-01-21, release date: 2013-02-06, Last modification date: 2023-11-08) |
Primary citation | Ohori, M.,Kinoshita, T.,Yoshimura, S.,Warizaya, M.,Nakajima, H.,Miyake, H. Role of a cysteine residue in the active site of ERK and the MAPKK family Biochem.Biophys.Res.Commun., 353:633-637, 2007 Cited by PubMed: 17194451DOI: 10.1016/j.bbrc.2006.12.083 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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