3W0J
Crystal Structure of Rat VDR Ligand Binding Domain in Complex with Novel Nonsecosteroidal Ligands
Summary for 3W0J
Entry DOI | 10.2210/pdb3w0j/pdb |
Related | 3W0G 3W0H 3W0I |
Descriptor | Vitamin D3 Receptor, Mediator of RNA polymerase II transcription subunit 1, (2S)-3-{4-[2-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propan-2-yl]-2-methylphenoxy}propane-1,2-diol, ... (4 entities in total) |
Functional Keywords | gene regulation, transcription |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Nucleus: P13053 Q15648 |
Total number of polymer chains | 2 |
Total formula weight | 30756.50 |
Authors | Shimizu, T.,Asano, L.,Kuwabara, N.,Ito, I.,Waku, T.,Yanagisawa, J.,Miyachi, H. (deposition date: 2012-10-30, release date: 2013-10-09, Last modification date: 2023-11-08) |
Primary citation | Asano, L.,Ito, I.,Kuwabara, N.,Waku, T.,Yanagisawa, J.,Miyachi, H.,Shimizu, T. Structural basis for vitamin D receptor agonism by novel non-secosteroidal ligands. Febs Lett., 587:957-963, 2013 Cited by PubMed: 23462137DOI: 10.1016/j.febslet.2013.02.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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