3VZM

Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose

3VZM の概要

• エントリーDOI: 10.2210/pdb3vzm/pdb
• 関連するPDBエントリー: 3VZJ 3VZK 3VZL 3VZN 3VZO
• 分子名称: Endo-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol (3 entities in total)
• 機能のキーワード: xylanase, gh-11 glycoside hydrolase, glycosyl-enzyme intermediate, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacillus circulans
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20686.27

構造登録者

Ludwiczek, M.L.,D'Angelo, I.,Yalloway, G.N.,Okon, M.,Nielsen, J.E.,Strynadka, N.C.,Withers, S.G.,McIntosh, L.P. (登録日: 2012-10-15, 公開日: 2013-05-08, 最終更新日: 2023-11-08)

• 主引用文献: Ludwiczek, M.L.,D'Angelo, I.,Yalloway, G.N.,Brockerman, J.A.,Okon, M.,Nielsen, J.E.,Strynadka, N.C.,Withers, S.G.,McIntosh, L.P.; Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase; Biochemistry, 52:3138-3156, 2013; PubMed: 23578322; DOI: 10.1021/bi400034m

実験手法

X-RAY DIFFRACTION (1.86 Å)