3VVH

X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in complex with an inhibitor and MgATP

Summary for 3VVH

• Entry DOI: 10.2210/pdb3vvh/pdb
• Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: kinase domain, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: Q02750
• Total number of polymer chains: 3
• Total formula weight: 116832.86

Authors

Kudo, N.,Kato, R.,Wakatsuki, S. (deposition date: 2012-07-24, release date: 2013-08-28, Last modification date: 2023-11-08)

• Primary citation: Kudo, N.,Kato, R.,Wakatsuki, S.; X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in complex with an inhibitor and MgATP; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)