3VVH

X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in complex with an inhibitor and MgATP

3VVH の概要

• エントリーDOI: 10.2210/pdb3vvh/pdb
• 分子名称: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: kinase domain, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: Q02750
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 116832.86

構造登録者

Kudo, N.,Kato, R.,Wakatsuki, S. (登録日: 2012-07-24, 公開日: 2013-08-28, 最終更新日: 2023-11-08)

• 主引用文献: Kudo, N.,Kato, R.,Wakatsuki, S.; X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in complex with an inhibitor and MgATP; To be Published,

実験手法

X-RAY DIFFRACTION (2 Å)