3VUD

Crystal structure of a cysteine-deficient mutant M1 in MAP kinase JNK1

3VUD の概要

• エントリーDOI: 10.2210/pdb3vud/pdb
• 関連するPDBエントリー: 3VUG 3VUH 3VUI 3VUK 3VUL 3VUM
• 分子名称: Mitogen-activated protein kinase 8, Peptide from C-Jun-amino-terminal kinase-interacting protein 1, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: map kinase, kinase domain, phosphorylation, atp binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm (By similarity): Q9UQF2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44142.92

構造登録者

Nakaniwa, T.,Kinoshita, T.,Inoue, T. (登録日: 2012-06-28, 公開日: 2013-02-13, 最終更新日: 2024-03-20)

• 主引用文献: Nakaniwa, T.,Fukada, H.,Inoue, T.,Gouda, M.,Nakai, R.,Kirii, Y.,Adachi, M.,Tamada, T.,Segawa, S.,Kuroki, R.,Tada, T.,Kinoshita, T.; Seven cysteine-deficient mutants depict the interplay between thermal and chemical stabilities of individual cysteine residues in mitogen-activated protein kinase c-Jun N-terminal kinase 1; Biochemistry, 51:8410-8421, 2012; PubMed: 23020677; DOI: 10.1021/bi300918w

実験手法

X-RAY DIFFRACTION (3.5 Å)