3VTT

High Resolution crystal structure of Dengue 3 Envelope protein domain III (ED3)

3VTT の概要

• エントリーDOI: 10.2210/pdb3vtt/pdb
• 分子名称: Envelope protein E, SULFATE ION (3 entities in total)
• 機能のキーワード: immunoglobin like domain, epitope presentation, cellular attachment, viral protein, structural protein
• 由来する生物種: Dengue virus type 3 (DENV-3)
• 細胞内の位置: Capsid protein C: Virion (Potential). Peptide pr: Secreted (By similarity). Small envelope protein M: Virion membrane; Multi-pass membrane protein (By similarity). Envelope protein E: Virion membrane; Multi- pass membrane protein (By similarity). Non-structural protein 1: Secreted. Non-structural protein 2A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P27915
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23438.70

構造登録者

Elahi, M.,Islam, M.M.,Kuroda, Y. (登録日: 2012-06-07, 公開日: 2012-12-26, 最終更新日: 2013-08-07)

• 主引用文献: Elahi, M.,Islam, M.M.,Noguchi, K.,Yohda, M.,Kuroda, Y.; High resolution crystal structure of dengue-3 envelope protein domain III suggests possible molecular mechanisms for serospecific antibody recognition; Proteins, 81:1090-1095, 2013; PubMed: 23239402; DOI: 10.1002/prot.24237

実験手法

X-RAY DIFFRACTION (1.7 Å)