3VPS

Structure of a novel NAD dependent-NDP-hexosamine 5,6-dehydratase, TunA, involved in tunicamycin biosynthesis

3VPS の概要

• エントリーDOI: 10.2210/pdb3vps/pdb
• 分子名称: NAD-dependent epimerase/dehydratase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: tunicamycins, biosynthesis, exo-glycal, dehydratase, rossmann fold, transferase
• 由来する生物種: Streptomyces chartreusis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72907.21

構造登録者

Wyszynski, F.J.,Lee, S.S.,Yabe, T.,Wang, H.,Gomez-Escribano, J.P.,Bibb, M.J.,Lee, S.J.,Davies, G.J.,Davis, B.G. (登録日: 2012-03-12, 公開日: 2012-04-18, 最終更新日: 2024-03-20)

• 主引用文献: Wyszynski, F.J.,Lee, S.S.,Yabe, T.,Wang, H.,Gomez-Escribano, J.P.,Bibb, M.J.,Lee, S.J.,Davies, G.J.,Davis, B.G.; Biosynthesis of nucleoside antibiotic tunicamycin proceeds via unique exo-glycal intermediates; To be published,

実験手法

X-RAY DIFFRACTION (1.9 Å)