3VG0

Antibody Fab fragment

Summary for 3VG0

• Entry DOI: 10.2210/pdb3vg0/pdb
• Related: 3v6o
• Descriptor: Monoclonal antibody 9F8 Fab fragment L chain, Monoclonal antibody 9F8 Fab fragment H chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: antibody fab fragment, immunoglobulin fold, n-linked glycosylation site, fab fragment, lbd domain of obr receptor, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 48406.72

Authors

Carpenter, B.,Hemsworth, G.R.,Ross, R.J.,Artymiuk, P.J. (deposition date: 2012-01-10, release date: 2012-03-14, Last modification date: 2023-09-13)

• Primary citation: Carpenter, B.,Hemsworth, G.R.,Wu, Z.,Maamra, M.,Strasburger, C.J.,Ross, R.J.,Artymiuk, P.J.; Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody.; Structure, 20:487-497, 2012; PubMed: 22405007; DOI: 10.1016/j.str.2012.01.019

Experimental method

X-RAY DIFFRACTION (2.27 Å)